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"Goodness knows" can mean everybody knows or nobody knows, depending on context.
If you hit the brick wall, you are facing a problem you are incapable of solving.
The wheat stands for the good and valuable, the chaff the bad and worthless.
If he had an axe to grind, he might well be saying one thing and meaning another.
Hence, “from the get go” means simply from the beginning, or from the very start.
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